We found that the CAR-T-cells demonstrated obvious TEM8-specific cytotoxic and cytokine launch reactions in vitro, but when injected into healthy C57BL6 and NSG mice they rapidly and selectively disappeared from your circulation and in most cases caused rapid toxicity

We found that the CAR-T-cells demonstrated obvious TEM8-specific cytotoxic and cytokine launch reactions in vitro, but when injected into healthy C57BL6 and NSG mice they…